In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections.

نویسندگان

  • Karen M Amsler
  • Todd A Davies
  • Wenchi Shang
  • Michael R Jacobs
  • Karen Bush
چکیده

In phase 3 clinical trials for ceftobiprole treatment of complicated skin and skin structure infections, 1,219 gram-positive and 276 gram-negative aerobic baseline pathogens were identified. Ceftobiprole inhibited all staphylococcal isolates, including methicillin-resistant strains, at MICs of </=4 mug/ml. Against Enterobacteriaceae and Pseudomonas aeruginosa isolates, the potency of ceftobiprole was similar to that of cefepime.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 52 9  شماره 

صفحات  -

تاریخ انتشار 2008